http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2554623-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_239b1fe8a19ef004b8c47c090a9c16d5 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N43-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D221-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D221-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 |
| filingDate | 2009-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b4e78c042240ac7ecec80644506ac84f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ddb269fe87548923df330d906b3376a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_353a97a720eb91987fcb24163056842f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_351c0f2a9b5dff7ce9977f225847a2a7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6615efb6f05eccbdafff171c4dbdf079 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6814609d1b4da938d9edad04795db9af http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_758337335d0482932384f462714fb7a6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d37d4ad3cae46b5cb55e6d0bfadc38e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a6d9feaf41a2d667649be78855b287e0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe2be1200351d654703fd6eed1cab5ca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d644cc061f0f86968071065c0236cb96 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3cb8b61405d83b9a9abb8511d86bd48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1485553a3771d6e9c3e1c555f277f70e |
| publicationDate | 2015-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2554623-T3 |
| titleOfInvention | Compounds of substituted 5,6-dihydro-6-phenylbenzo [f] isoquinolin-2-amine |
| abstract | A compound having formula I: ** Formula ** or a salt, solvate or hydrate thereof, wherein: X is N, or CRc; each Rp is independently halogen, hydroxyl, substituted or unsubstituted C1-C6 alkoxy, substituted or unsubstituted C1-C6 alkyl; one of Rz and Rz, is H and the other is - substituted or unsubstituted C6-C10-1-aryl C6-C10 or substituted or unsubstituted (CH2) 1-C6-C10 heteroaryl or Rz and Rz, together with the atom of Carbon to which they are attached form a substituted or unsubstituted 10-8 membered heterocycle, optionally containing 0-4 additional heteroatoms selected from N, O, and S; R1 and R2 are each independently H, -T1-Q1, or R1 and R2, together with the nitrogen atom to which they are attached, form a substituted or unsubstituted 5-10 membered heterocycle comprising 0-4 additional selected heteroatoms of N, O and S; T1 and T3 are each independently substituted or unsubstituted C1-C6 alkyl linker, or a bond; Q1 is H, hydroxyl, halogen, substituted or unsubstituted C1-C6 alkyl, substituted or unsubstituted C1-C6 alkoxy, substituted or unsubstituted C6-C10 aryloxy, unsubstituted amino, substituted or unsubstituted C6-C10 arylamino, C1 alkylamino -Substituted or unsubstituted C6, substituted or unsubstituted di-C1-C6 alkylamino, substituted or unsubstituted C6-C10 aryl, substituted or unsubstituted heteroaryl comprising one or two 5- or 6-membered rings and 1-4 heteroatoms selected from N, O and S, substituted or unsubstituted C3-C10 carbocycle, substituted or unsubstituted heterocycle comprising one or two 5- or 6-membered rings and 1-4 heteroatoms selected from N, O and S, -C (O) R7 , - C (O) OR7, or -C (O) NR7R8; R7 and R8 are each independently -T3-Q3, or R7 and R8, together with the nitrogen atom to which they are attached, form a substituted or unsubstituted 5- to 8-membered heterocycle optionally containing from 0-4 additional selected heteroatoms of N, O and S; Q3 is H, hydroxyl, halogen, substituted or unsubstituted C1-C6 alkyl, substituted or unsubstituted C1-C6 alkoxy, substituted or unsubstituted C6-C10 aryloxy, unsubstituted amino, substituted or unsubstituted C1-C6 alkylamino, di- substituted or unsubstituted C1-C6 alkylamino, substituted or unsubstituted C6-C10 aryl, substituted or unsubstituted heteroaryl comprising one or two 5- or 6-membered rings and 1-4 heteroatoms selected from N, O and S, C3 carbocycle- Substituted or unsubstituted C10, or substituted or unsubstituted heterocycle comprising one or two 5- or 6-membered rings and 1-4 heteroatoms selected from N, O and S; Rc is H, cyano, halogen, or -C (O) NR14R15; R14 and R15 are each independently H, or substituted or unsubstituted C1-C6 alkyl; 1 is 0, 1, 2, or 3; n is 0, 1, 2, 3 or 4 wherein: said substituted alkoxy is substituted alkenyl, alkynyl, halogen, hydroxyl, alkylcarbonyloxy, arylcarbonyloxy, alkoxycarbonyloxy, aryloxycarbonyloxy, carboxylate, alkylcarbonyl, arylcarbonyl, alkoxycarbonyl, aminocarbonyl, alkylaminocarbonyl, dialkylaminocarbonyl , alkylthiocarbonyl, alkoxy, phosphate, phosphonate, phosphinate, amino (including alkylamino, dialkylamino, arylamino, diarylamino, and alkylarylamino), acylamino (including alkylcarbonylamino, arylcarbonylamino, carbamoyl, and ureido), amidino, imino, sulfhydryl, alkylthio, arylthio, thiocarbonyl. sulfates, alkylsulfinyl, sulfonate, sulfamoyl, sulfonamido, nitro, trifluoromethyl, cyano, azido, heterocyclyl, alkylaryl, or an aromatic or heteroaromatic moiety; said substituted alkyl, substituted alkylamino or substituted dialkylamino is substituted with alkyl, alkenyl, alkynyl, halogen, hydroxy, alkylcarbonyloxy, arylcarbonyloxy, alkoxycarbonyloxy, aryloxycarbonyloxy, carboxylatyl, alkylabonyloxycarbonyloxycarbonyloxycarbonyloxycarbonyloxycarbonylaryl phosphonate, phosphinate, amino (including alkylamino, dialkylamino, arylamino, diarylamino, and alkylarylamino), acylamino (including alkylcarbonylamino, arylcarbonylamino, carbamoyl, and ureido), amidino, imino, sulfhydryl, alkylthio, arylthio, thiocarboxylate, sulfate, alkylsulfnyl, sulfonate, sulfonamido, nitro, trifluoromethyl, cyano, azido, heterocyclyl, alkylaryl, or an aromatic or heteroaromatic moiety; and said substituted aryl, substituted heteroaryl, substituted heterocycle, substituted aryloxy, arylamino substituted and substituted carbocycle substituted in one or more positions with alkyl, alkenyl, alkynyl, halogen, hydroxyl, alkylcarbonyloxy, arylcarbonyloxy, alkoxycarbonyloxy, aryloxycarbonyloxy, carboxylate, alkylcarbonyl , alkynylcarbonyl, aralkylaminocarbonyl, alkenylaminocarbonyl, alkylcarbonyl, arylcarbonyl, aralkylcarbonyl, alkenylcarbonyl, alkoxycarbonyl, aminocarbonyl, alkylthiocarbonyl, phosphate, amino-alkylamino, (alkylamino, dialkylamino,) alkylamino,). carbamoyl and ureido), amidino, imino, sulfhydril, alkylthio, arylthio, thiocarboxylate, sulfates, alkylsulfinyl, sulfonate, sulfamoyl, sulfonamido, nitro, trifluoromethyl, cyano, azido, heterocyclyl, alkylaryl, or an aromatic or heteroaromatic moiety. |
| priorityDate | 2008-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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Total number of triples: 1728.