abstract |
Isolated human IL-18R1 binding antibody and characterized in that it comprises as the heavy chain variable region CDRs a CDRH1 region of sequence SEQ ID No. 2 or SEQ ID No. 10, a CDRH2 region of sequence SEQ ID No. 3 and a CDRH3 region of sequence SEQ ID No. 4, and as a light chain variable region CDR, a CDRL1 region of sequence SEQ ID No. 6, a CDRL2 region of sequence SEQ ID No. 7 and a CDRL3 region of sequence SEQ ID No. 8. |