| abstract |
Compound according to formula (I) or (II) ** Formula ** in which R1 and R1 'are independently selected from the group consisting of H, C1-5 alkyl, and C0-1-aryl alkylene; R2 and R2 'are independently selected from the group consisting of H, C1-5 alkyl, and C0-1 alkylene-aryl; R3 and R3 'are independently selected from the group consisting of H, C1-5 alkyl, and C0-1alkylene-aryl; R4 and R4 'are independently selected from the group consisting of H, C1-5 alkyl, and C0-1alkylene-aryl; R5 is selected from the group consisting of C0-5 O-alkyl, C1-5 O-fluoroalkyl, OC (O) C1-5 alkyl, C2-3N O-alkylene (C0-5 alkyl) 2 in which the C0-5 alkyl can be the same or different, NH-C0-5 alkyl, N (C1-5 alkyl) 2 in which the C1-5 alkyl can be the same or different, N ( C0-5alkyl) C (O) C1-5alkyl, NHaryl, NHheteroaryl, a 3- to 8-membered non-aromatic heterocycle that is connected by a substitutable heteroatom of said non-aromatic heterocycle, C0-5 S-alkyl, S (O) C0-5alkyl, SO2-C0-5alkyl, and N (C0-C3alkyl) SO2-C1-C5alkyl; R6 is selected from the group consisting of H, C1-5 alkyl, C1-5 fluoroalkyl, and a C3-8 non-aromatic carbocycle; at least one of R2, R2 ', R3, R3', R4 and R4 'comprises a carbon atom; and said heteroaryl is a 5-membered heteroaryl, or a 6-membered heteroaryl; as a free base, an acid in its uncharged protonated form, a pharmaceutically acceptable addition salt, solvate, solvate of a salt thereof, a pure diastereomer, a pure enantiomer, a diastereomeric mixture, a racemic mixture, a scemic mixture, a corresponding tautomeric form resulting from a hydrogen shift between two heteroatoms and / or the corresponding tautomeric form resulting from a ketoenolic tautomerization. |