| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e0ac97cf34efaa5edc0c2cf9722c2b02 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-495
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-65 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-495
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate |
2008-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2015-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f4a036d5a25a831edf5af03174c3650
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fbdb1109921cce59821ed4d4d7adedd4 |
| publicationDate |
2015-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
ES-2552018-T3 |
| titleOfInvention |
Construction of a latency-associated protein containing an aggrecanase-sensitive cleavage site |
| abstract |
A fusion protein comprising a latency-associated peptide (LAP) which is the precursor domain of TGFβ-1, -2, -3, -4 or -5 and a pharmaceutically active principle in which the LAP and the pharmaceutically active principle active are linked by an amino acid sequence comprising a proteolytic cleavage site by an aggrecanase cleaved by ADAMTS-4 (aggrecanase-1) or ADAMTS-5 (aggrecanase-2). |
| priorityDate |
2007-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |