http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2550035-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b03b63dcb77a2269515f7c17cdee4a66 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0056 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5073 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5084 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4178 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2077 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-20 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4178 |
| filingDate | 2007-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f268cb6f3982ed7fbb3a33db18503fd8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b6e485ac609cf337bc87d08c47bd76e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9a09b9bf8b8d8596b3fa062260e3b7e |
| publicationDate | 2015-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2550035-T3 |
| titleOfInvention | Drug delivery systems comprising a weakly basic serotonin 5-HT3 selective blocking agent and organic acids |
| abstract | A multiparticulate pharmaceutical dosage form comprising one or more populations of controlled pulsatile release (LPC) beads of a weakly basic drug; wherein the weakly basic drug comprises a selective serotonin blocking agent 5-HT3 containing nitrogen (N), or a pharmaceutically acceptable salt thereof, having a pKa in the range of about 5 to 14 and a solubility of no greater than about 200 µg / ml at pH 6.8; wherein the LPC beads comprise organic acid core particles comprising at least one pharmaceutically acceptable organic acid, having a barrier coating with an LS (sustained release) polymeric membrane comprising a non-water soluble polymer alone or in combination with a water-soluble polymer or an enteric polymer, in which the weakly basic drug is layered and further coated with a time-delayed membrane, so that both the organic acid and the weakly basic drug have comparable drug release profiles; and wherein the weakly basic drug and organic acid are not in contact with each other in the dosage form. |
| priorityDate | 2006-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 101.