http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2548414-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf32b60391b469c41e86c353437f5751 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2012-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b67375248e51f68add6c4a62dc2c4b36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b998dd266091fdccaf9e4300b1414210 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aca5c30d68ed3ba04448f2fcfda75c3e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92a03cced6829526c69c62d866650690 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_50a944871e2f47bd366d3a3e2a64e310 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d211f7baa01b7827cb3cc950312d454 |
| publicationDate | 2015-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2548414-T3 |
| titleOfInvention | Novel pyrimidine pyrrolo derivatives |
| abstract | A compound of formula (I) or a pharmaceutically acceptable salt thereof; ** Formula ** wherein, R 1 is hydrogen, C 1 -C 6 alkyl optionally substituted by hydroxy; R2 is hydrogen or halogen; R3 is hydrogen or halogen; R4 is hydrogen, R5 is phenyl optionally substituted by halogen; SF5; NR6R7; hydroxy; C1-C6 alkoxy; C1-C6 alkenyl; C1-C6 alkyl carbonyl; C1-C6 alkyl optionally substituted by hydroxy, halogen, or C1-C6 alkoxy; or C3-C6 cycloalkyl optionally substituted by halogen, hydroxy, or C1-C6 alkyl optionally substituted by halogen; or R5 is a 4-14 membered mono- or bicyclic heterocyclyl or heteroaryl ring system comprising 1, 2 or 3 heteroatoms selected from N, S and O with that ring being optionally substituted by halogen; hydroxy; C1-C6 alkoxy optionally substituted by hydroxy or halogen; or C1-C6 alkyl optionally substituted by hydroxy or halogen; or R4 and R5 together with the atoms to which they are attached form a piperidone ring, optionally comprising a fused phenyl ring, any such ring being optionally substituted by C1-C6 alkyl, C1-C6 alkoxy, or C3-C6 cycloalkyl, each of which substitution members may optionally be substituted by halogen or hydroxy; R6 and R7 are independently selected from hydrogen or C1-C6 alkyl; or R6 and R7 together with the nitrogen atom to which they are attached form a 4-8 membered saturated azacycloalkane ring, optionally substituted by halogen, hydroxy or C1-C6 alkyl; X is O, S (O) n where n is 0, 1 or 2, or is absent; where q is 2 or 3, and R10 is or X is CH or N; and R10 is hydrogen, hydroxy, -NR6R7, -CO-R11, -S (O) p-R12 where p is 1 or 2, R 11 is C1-C6 alkyl optionally substituted by hydroxy, cyano, halogen, carboxy or C1 -C6 alkoxycarbonyloxy; or NR6R7; and R12 is C1-C6 alkyl or NR6R7. |
| priorityDate | 2011-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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