| abstract |
Synthesis procedure of the compound of optically pure formula (Ia): ** Formula ** by enantioselective enzymatic esterification of racemic or non-optically pure acid of formula (X): ** Formula ** with the aid of a Candida antarctic lipase or Pseudomonas fluorescens, in a mixture of ROH alcohol, where R represents a linear or branched (C1-C6) alkyl group, and an organic cosolvent, in a concentration of 5 to 500 g / l of the compound of formula (X) per liter of solvent mixture, with an I / O ratio of 10/1 to 1/100, at a temperature of 25ºC to 40ºC. |