http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2545260-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1224e3c07b7cc5684ee81d9e1e5ee15c |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N24-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-10 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-1815 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-055 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-055 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B60-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-10 |
| filingDate | 2005-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76f7921e42522d26f5934de3f4c5a763 |
| publicationDate | 2015-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2545260-T3 |
| titleOfInvention | Composition comprising triarylmethyl radical, useful in MRI diagnosis |
| abstract | Method for producing a liquid composition comprising hyperpolarized 13C-pyruvate, said method comprising a) forming a liquid mixture comprising a radical of formula (I), 13C-pyruvic acid and / or 13C-pyruvate and freezing the mixture; ** Formula ** in which M represents hydrogen or an equivalent of a cation; and R1 which is the same or different represents a hydroxylated and / or alkoxylated C1-C4 hydrocarbon group, straight or branched chain b) enhancing the 13C nuclear polarization of pyruvic acid and / or pyruvate in the mixture by DNP; c) add a buffer and a base to the frozen mixture to dissolve it and convert 13C-pyruvic acid into a 13C-pyruvate to obtain a liquid composition or, when only 13C-pyruvate is used in step a), add a buffer a the frozen mixture to dissolve it to obtain a liquid composition; and d) optionally removing the radical and / or reaction products thereof from the liquid composition. |
| priorityDate | 2004-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 100.