http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2544573-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c2d3c9703ba52c9f6d121388057058bf |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-17 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 |
| filingDate | 2012-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f403cd15d4c34f072a34d3fb30b06a1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4aace2c38186291d359eef0e807eb3df |
| publicationDate | 2015-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2544573-T3 |
| titleOfInvention | High-affinity dimeric inhibitors of PSD-95 and its use for the treatment of ischemic brain damage and pain |
| abstract | A compound comprising a first peptide linked to a second peptide by a linker, wherein the first and second peptide comprise at least four amide-linked residues having a YTXV or YSXV sequence, wherein a. Y is selected from E, Q, and A, and b. X is selected from A, Q, D, N, N-Me-A, N-Me-Q, N-Me-D, and N-Me-N, and in which the linker comprises PEG and, in which at least one oxygen atom of the PEG is replaced by a nitrogen atom to provide NPEG, in which a cellular penetration peptide (CPP) is attached to the nitrogen atom of the linker through an amide bond, and in which the CPP comprises at least 4 amino acid residues selected from arginine and / or lysine. |
| priorityDate | 2011-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 81.