http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2544542-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37f4922dfb7777b019e504b885211b8e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_06e7b5dbbdda3502cb8e3ab048fbf05b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f028281f3d001fea61a2bc72288984e9 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D249-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D249-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-056 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-357 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4192 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7028 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7056 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7056 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4192 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-056 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D249-06 |
| filingDate | 2012-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8dda88a6072d4bc4182bc8f99b14f22c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3b7e19913966bb680423c537c4163b5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eb0b42bbefde0c37e845cb52693206c9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b8f46be72c84574ad10c86e652773dcd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb59e4c529c76c9b25ca4d80197fee74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8fbd535717f68c35e8ee09ffc963b623 |
| publicationDate | 2015-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2544542-T3 |
| titleOfInvention | Acadesin derivatives, products and compositions that comprise them, their therapeutic uses and their synthesis procedures |
| abstract | Compounds of the general formula: ** Formula ** in which: - R1 is selected from a · cyclic pentose group in a furyic form with free OH groups or possibly substituted with one or more mono-, bi- or triphosphate, acetyl , isopropylidene, benzoyl or paratoluoyl, · a hexose group in pyranic form with free OH groups or possibly substituted with one or more mono-, bi- or triphosphate or acetyl groups, · a naphthyl group, optionally substituted with one or several alkyl groups or substituted amino having 1 to 4 carbon atoms, · a benzyl group optionally substituted with one or more alkyl or substituted amino groups having 1 to 4 carbon atoms, · phenyl, biphenyl, heteroaryl groups; - R2 is selected from · an amide group -CONH2, -CONHMe, -CONHEt, -CON (Me) 2, -CON (Et) 2, · an acid or ester group -CO2H, CO2Me, CO2Et, a cyano group or amidine -CN, -C (NH2) NH, -C (NHMe) NH, -C (NHEt) NH, · a phenyl group optionally substituted by a halogen selected from CI, Br, I and F, · a thiophene group, · A linear or branched carbon chain having 3 to 10 carbon atoms, or · a methoxynaphthalene group; and - R3 is selected from: · a halogen group, · a furan or -CO-furan group, · a thiophene or -CO-thiophene or -C≡C-thiophene group, · a toluoyl group, · an acetylene group, · A -CO- (CH2) n-CH3 group, with n between 2 and 9, · a phenyl or -C≡C-phenyl group, optionally substituted with a halogen, · a -C≡C-CO2Me group, - C≡C-CO2Et, -C≡C-CONH2, · a group -C≡C- (CH2) 6CH3, or · a group -C> = C-2-methoxynaphthalene; its racemic, enantiomers, diastereoisomers and mixtures thereof, its tautomers and pharmaceutically acceptable salts, for use as a medicine. |
| priorityDate | 2011-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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