http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2543393-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3120ae9cab5bb4831f0cc16288966367 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-62 |
| filingDate | 2008-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_52a221a652e248b1367c58a6742ec75e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4821342d612e35406478646ac0b71d56 |
| publicationDate | 2015-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2543393-T3 |
| titleOfInvention | Insulin derivative |
| abstract | An insulin derivative having a formula ** Formula ** where Ins is a residue of parental insulin and Q1-Q2- [CH2] n-X1- [CH2] n-Q3- [CH2] n -X2- [CH2 ] n-Q4- [CH2] n-X3- [CH2] n-Q5- [CH2] nZ is a substituent and where Ins is attached to the substituent by an amide bond between the α-amino group of the N-terminal amino acid residue from the B chain of Ins or an ε-amino group of a Lys residue present on the A or B chain of Ins and a CO group at Q1 or Q2 of the substituent; each n is independently 0, 1, 2, 3, 4, 5 or 6; Q1 is: - an amino acid residue, a residue that forms, with its carboxylic acid group, an amide group together with the α-amino group of the N-terminal amino acid residue of the B chain of Ins or together with the ε-amino group of a Lys residue present on the A or B chain of Ins, or - a chain consisting of two, three or four α-amino acid residues as specified above linked to each other by amidic bonds, chain which is linked - by a bond amidic - to the α-amino group of the N-terminal amino acid residue of the B chain of Ins or to the ε-amino group of a Lys residue present on the A or B chain of Ins, or - a Q2 bond is: -CO- (CH2) 2-NH- (CH2) 2-, or -CO-CH2-NH-CH2-; Q3 is: - (CH2) m- where m is 12, 13, 14, 15 or 16; X1 can be: - O; - -C> = O; - a link; - NCOR1, where R1 can be H, -CH3 or - (CH2) 1-6-CH3; or - ** Formula ** or where R is hydrogen, C1-3-alkyl, C2-3-alkenyl or C2-3-alkynyl; Q4, Q5, X2 and X3 are bonds and all n are zero, and Z is: -COOH. |
| priorityDate | 2007-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 172.