http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2543160-T3
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_577821cf81fda3e1088e6ed08bcd136b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8528ff66470c896b6da8ed059464e31f |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-085 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-142222 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-143333 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
filingDate | 2004-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2015-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a0ece0064debbc5d731a546d800313b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd24e8bbd00d9009c5426b3a375b48b4 |
publicationDate | 2015-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-2543160-T3 |
titleOfInvention | A serum marker to measure liver fibrosis |
abstract | A method for distinguishing fibrotic early cirrhotic liver disease in a mammal, comprising: a) generating a serum N-glycol profile of N-linked carbohydrates or oligosaccharide fragments derived therefrom, or labeled derivatives thereof N-linked carbohydrates or said fragments, or characteristics of said N-linked carbohydrates or said fragments that are determined by the structure of said N-linked carbohydrates or said fragments; said N-linked carbohydrates or said fragments present in or obtained from total serum proteins that are present in or isolated from a blood serum sample of said mammal, and b) measuring in the profile of step a) the amount of at least one N-linked carbohydrate or an oligosaccharide fragment derived therefrom or a labeled derivative of said N-linked carbohydrate or said fragment, or a characteristic of at least one N-linked carbohydrate or fragment derived therefrom present in said N-linked carbohydrate profile, and c) comparing the measured data obtained in step b) with measured data obtained from profiles derived from hepatic fibrosis-free mammals in order to distinguish early cirrhotic liver disease of fibrotic or, compare the data obtained in step b) with previously measured data in said mammal in order to distinguish cirrhotic liver disease. mprana fibrotic and d) attribute the results of the comparison obtained in stage c) to distinguish early cirrhotic liver disease from fibrotic. |
priorityDate | 2003-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 963.