http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2542326-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f2d3599fb8f8f479dba95ca9bb504884 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D251-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D251-50 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D251-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D251-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D251-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D251-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D251-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D251-50 |
| filingDate | 2001-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de0fb6ce5e0b1f01b01258f2235ec391 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c405d897badcc48d53d95df6e39ea66d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_807dce8e759f1bfc958243c904f71184 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab0b18c5148a765a43227d65efb3e200 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ef7647e0b98b44dd42f7c98bcb3e043 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_193b4dcbd43f650fcdf85429cf5a38ab http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_31cec5680f2d781d5c9d869ccf79b776 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd353bc9b009350567061c9d0ce4b4a2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ead0056a52b5691aab454adfafa5fcc4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f579a68b8ca43d1c80be69d454c7e4bb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_365d6c008ac0e8dce16ca0477eba79ba |
| publicationDate | 2015-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2542326-T3 |
| titleOfInvention | HIV replication inhibitors |
| abstract | A compound of the formula: ** Formula ** an N-oxide, a pharmaceutically acceptable addition salt, a quaternary amine, and a stereochemically isomeric form thereof, where -b1> = b2-C (R2a)> = b3- b4> = represents a bivalent radical of the formula: -CH> = CH-C (R2a10)> = CH-CH> = (b-1); -N> = CH-C (R2a)> = CH-CH> = (b-2); -CH> = N-C (R2a)> = CH-CH> = (b-3); -N> = CH-C (R2a)> = N-CH> = (b-4); -N> = CH-C (R2a)> = CH-N> = (b-5); -CH> = N-C (R2a20)> = N-CH> = (b-6); -N> = N-C (R2a)> = CH-CH> = (b-7); R1 is hydrogen; aryl; formyl; C1-6alkylcarbonyl; C1-6alkyl; C1-6 alkyloxycarbonyl; formyl-substituted C1-6alkyl, C1-6alkylcarbonyl, C1-6alkyloxycarbonyl, C1-6alkylcarbonyloxy; C1-6 alkyloxy-C1-6 alkylcarbonyl substituted with C1-6 alkyloxycarbonyl; q is 0, 1, 2; or when possible q is 3 or 4; R2a is cyano, aminocarbonyl, mono- or di- (methyl) aminocarbonyl, C1-6 alkyl substituted with cyano, aminocarbonyl or mono- or di- (methyl) aminocarbonyl, C2-6 alkenyl substituted with cyano or C2-6 alkynyl substituted with cyano; each R2 is independently hydroxy, halo, C1-6 alkyl optionally substituted with cyano or -C (> = O) R6, C3-7 cycloalkyl, C2-6 alkenyl optionally substituted with one or more halogen or cyano atoms , C2-6 alkynyl optionally substituted with one or more halogen or cyano atoms, C1-6 alkyloxy, C1-6 alkyloxycarbonyl, carboxyl, cyano, nitro, amino, mono- or di- (C1-6alkyl) amino, polyhalomethyl, polyhalomethyloxy, polyhalomethylthio, -S (> = O) pR6, -NHS (> = O) pR6, -C (> = O) R6, -NHC (> = O) H, -C (> = O) NHNH2, - NHC (> = O) R6, -C (> = NH) R6 or a radical of the formula: ** Formula ** in which: each A1 is, independently, N, CH or CR6; and A2 is NH o, S or NR6; p is 1 or 2; L is C1-10 alkyl, C2-10 alkenyl, C2-10 alkynyl, C3-7 cycloalkyl, each of said groups being substituted with one or two substituents independently selected from: * C3-7 cycloalkyl, * indolyl or isoindolyl, each optionally substituted with one, two, three or four substituents each independently selected from halo, C1-6 alkyl, hydroxy, C1-6 alkyloxy, cyano, aminocarbonyl, nitro, amino, polyhalomethyl, polyhalomethyloxy and C1-6alkylcarbonyl, * phenyl, pyridyl, pyrimidinyl, pyrazinyl or pyridazinyl, each of said aromatic rings being optionally substituted with one, two, three, four or five substituents each independently selected among the defined substituents at R2; or L is -X1-R3 or -X2-Alk-R4, wherein: R3 is 2,4,6-trisubstituted phenyl, each of the substituents being independently selected from the substituents defined in R2; Alk is C1-4 alcanediílo; R4 is phenyl, pyridyl, pyrimidinyl, pyrazinyl or pyridazinyl, each of said aromatic rings being optionally substituted with one, two, three, four or five substituents each independently selected from among the substituents defined in R2; and X1 or X2 is each, independently, -NR7-, -NH-NH-, -N> = N-, -O-, -C (> = O) -, -CHOH-, -S-, -S (> = O) p-. |
| priorityDate | 2000-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 379.