abstract |
Composition comprising a block copolymer associated with a polynucleotide, the block copolymer comprising a first, a second and a third block of different composition, the first block being a block of hydrophilic polymer, the second block being located between the first and the first. third block and associated with the polynucleotide, the third block being a block of hydrophobic polymer comprising anionic repeating units, the anionic repeating units having a population of anions as substituents thereof which varies in number in a pH dependent manner, the population being greater at pH 7.4 than at pH 5, in which at least 90% of the repeating units of the first, second and third blocks are not amino acid residues linked by a peptide bond. |