http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2538467-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e5f2d89a8c9d985b85a5d6512df76351 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-2821 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-136 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2009-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf9d9cb4bef7e7efa09c48a786b9e981 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3df1debffe25ce907f1a3e4663841a3 |
| publicationDate | 2015-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2538467-T3 |
| titleOfInvention | Stimulus-induced genomic profile markers that mark Alzheimer's disease |
| abstract | A diagnostic method for Alzheimer's disease, said method comprising the steps of: i) contacting a population of test skin fibroblast cells obtained from a subject suspected of having Alzheimer's disease with an agent that is an activator of protein kinase C; and ii) detecting changes in the expression of one or more genes in test skin fibroblast cells when one or more genes in control skin fibroblast cell cells obtained from an individual without Alzheimer's disease, in which a change in gene expression in test skin fibroblast cells compared to gene expression in control skin fibroblast cells indicates that the individual has Alzheimer's disease, the change in the gene expression detected in the test skin fibroblast cells compared to the control skin fibroblast cells is an increase in gene expression or a decrease in gene expression, said one or more genes showing a decrease in gene expression is selected from the group comprising genes having the gene bank accession numbers NM_020979.1, BC000284.1, NM_001037.1, NM_003832.1, NM_022 078.1, AI492892, T86629, AW418666, AW468880, NM_005399.1, BF433071, NM_152902.1, AI679073, NM_006902.2, BF000166, NM_001684.1, AI813654, AI492892, and said one or more genes that show an increase in gene expression are selected from the group comprising the genes that have the gene bank accession numbers AW238632, AW611729, AV740879, AA639752, AF088033, AW182938, AL031282, BF430956, AW956580, AI394529, AL137364.1, NM_001452.1, BF113616, AF056433, NM_014574.1, NM_013233.1, AI017106, AI927770, BG291787, AI760760, NM_003760.2, NM_022346.1, AI816281, NM_016374.2, AW963328, AA147933, BC005503.15. 1, R60866, AI823905, and NM_018098.1. |
| priorityDate | 2008-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 283.