http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2537610-T3
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7326b5c97dc18dd298e8b4e372a6f15f |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D489-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D489-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D489-12 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D489-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D489-08 |
filingDate | 2011-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2015-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92d7dbcd714e6934b91bc521baf66e20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_05c4fe79df0b59a88541552f17f04124 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a8b604fa993d0a038f5f86ed0547c8a |
publicationDate | 2015-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-2537610-T3 |
titleOfInvention | Process for the N-desalkylation of tertiary amines |
abstract | A method for N-demethylating a compound of formula (6) ** Formula ** comprising (a) contacting the compound of formula (6) with a compound of formula (2) ** Formula ** in a solvent for providing a compound of formula (7) ** Formula ** and (b) converting the compound of formula (7) into a compound of formula (8) ** Formula ** in which the solvent comprises from 80% vol to 100% by volume or consists of a tertiary alcohol selected from the group consisting of tert-amyl alcohol, tert-butyl alcohol, 3-methyl-3-pentanol, 2,3-dimethyl-3-pentanol, 3-ethyl-3- pentanol, 2-methyl-2-hexanol, and mixtures of two or more of these; the link ------ 7.8 is a single link or a double link; R9 and R11 are each independently selected from the group consisting of -OH, -H, and -OR15; R9 'and R11' are each independently selected from the group consisting of -OH, -H, -OR15, and -OC (O) OR4; R10 is selected from the group consisting of> = O, -OH,> = CH2, -H, and -OR15; R10 'is selected from the group consisting of> = O, -OH,> = CH2, -H, -OR15, and -OC (O) OR4; R15 is an oxygen protecting group; R4 is selected from the group consisting of -C1-C6-alkyl, -C2-C6-alkenyl, -C2-C6-alkynyl, aryl, and heteroaryl, each being unsubstituted or substituted with 1, 2, 3 , 4, or 5 independently selected R5 groups; each R5 is independently selected from the group consisting of -OH, -Cl, Br, -I, -NH2, -CN, -O-(C1-C6) alkyl, and phenyl; and X is selected from the group consisting of -Cl, -Br, -I, mesylate, and tosylate. |
priorityDate | 2010-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 162.