http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2537591-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-407 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-403 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-00 |
| filingDate | 2012-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e698493b7081e0866d522a049b201ae9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4535a4eae8bb559ed558aea0639c638c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d2e92cf4711c6a42494f81603f2bd2e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1f654ec66a622f878ccae27106181be http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_589e637640a348954dfd7929f1080661 |
| publicationDate | 2015-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2537591-T3 |
| titleOfInvention | New compounds hexahydrocyclopentapyrrolone, hexahydropyrrolopyrrolone, octahydropyrrolopyridinone and octahydropyridinone |
| abstract | Compounds of formula (I): ** Formula ** R1 is alkyl, haloalkyl, alkoxyalkyl, haloalkoxyalkyl, hydroxyalkyl, phenyl, substituted phenyl, phenylalkyl, substituted phenylalkyl, phenoxyalkyl, phenoxyalkyl, heteroaryl, substituted heteroaryl, heteroaryl, alkyl or heteroaryl, heteroaryl, alkyl wherein substituted phenyl, substituted phenylalkyl, substituted phenoxyalkyl, substituted heteroaryl and substituted heteroarylalkyl is substituted with one to three substituents independently selected from alkyl, cycloalkyl, cycloalkylalkyl, halo, haloalkyl, hydroxy, hydroxyalkyl, alkoxy, alkoxyalkyl, haloalkoxy, hydroxyhaloalkyl and alcoxihaloalquilo , R2 is phenyl, substituted phenyl, heteroaryl or substituted heteroaryl, in which substituted phenyl and substituted heteroaryl are substituted with one to three substituents independently selected from alkyl, cycloalkyl, cycloalkylalkyl, halogen, haloalkyl, hydroxy, hydroxyalkyl, alkoxy, alkoxyalkyl, haloalkoxy, hydroxyhaloalkyl and alkoxyhaloalkyl, R3 is hydrogen, hydroxy or alkoxy, where, in the case where R3 is hydroxy or alkoxy, E is -C (R5R6) -, R4 is hydrogen, alkyl or cycloalkyl, R5 is hydrogen, alkyl or cycloalkyl, R6 is hydrogen, alkyl or cycloalkyl, n is 1 or 2; A is -N or -CR3; E is a bond or -C (R5R6) -, G is -O-, -NR4-, -CH (OH) -, -C (O) -, -C (O) O-, -C (O) NR4 -, -S (O) 2-, -S (O) 2NR4- or a bond, in which, in case E and G are a bond, R1 is directly linked to A, or pharmaceutically acceptable salts of thereof, in which: the term "alkyl" refers to a monovalent linear or branched saturated hydrocarbon group with 1 to 7 carbon atoms, the term "cycloalkyl" refers to a monovalent saturated monocyclic or bicyclic hydrocarbon group with 3 to 10 ring carbon atoms, the term "heteroaryl" refers to a monovalent aromatic mono- or bi-cyclic ring system with 5 to 12 ring atoms, comprising 1, 2, 3 or 4 heteroatoms selected from N, O and S, the remaining ring atoms being carbon. |
| priorityDate | 2011-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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