| abstract |
A pharmaceutical formulation comprising a benzamide derivative represented by the formula (1): ** Formula ** in which A represents a structure shown by any one of the formula (2): ** Formula ** or a pharmaceutically acceptable salt thereof, an excipient selected from the group consisting of lactose, lactose anhydride, D-mannitol, corn starch and crystalline cellulose, a lubricant selected from the group consisting of magnesium stearate, calcium stearate, stearic acid and talc, a disintegrant selected from the group consisting of partially pregelatinized starch, calcium carmellose and sodium carboxymethyl starch, and one or more of one selected from the group consisting of an amino compound and an inorganic basic substance, wherein the amino compound is one or more of one selected from the group consisting of tris (hydroxymethyl) aminomethane, monoethanolamine, diethanolamine, triethanolamine, diisopropanolamine, triisopropanolamine, aminoacet Ato dihydroxyaluminium, arginine, creatinine, sodium glutamate, glycine, L-arginine Lglutamate and carbacol, and the inorganic basic substance is one or more of one selected from the group consisting of sodium carbonate, potassium carbonate, ammonium carbonate, sodium bicarbonate, bicarbonate potassium, sodium hydroxide, disodium phosphate and ammonia. |