abstract |
Non-propellant sublingual fentanyl formulation comprising discrete liquid droplets of an effective amount of fentanyl in a pharmaceutically acceptable liquid carrier, said drops having an average diameter of at least about 10 micrometers, wherein said fentanyl formulation is configured to the sublingual supply and in which the sublingual formulation comprises from about 0.1% to about 0.8% by weight of fentanyl or a pharmaceutically acceptable salt thereof, from about 20% to about 60% by weight of ethanol; and from about 4% to about 6% by weight of propylene glycol. |