http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2533851-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2f85b08f8307c2c093183b1254729485 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-405 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-3211 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-306 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-4816 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-3241 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-303 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-67 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-675 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-662 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-655345 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-301 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-352 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-662 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-675 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-485 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-197 |
| filingDate | 2009-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3a3a6f3a56d7edf7a3c0d1c54ea4cab http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e3aacbd213a2560510989991fa1a18d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07e09e22848d58416f0254e5b2c215bb |
| publicationDate | 2015-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2533851-T3 |
| titleOfInvention | Aminophosphine derivatives useful in the treatment of pain |
| abstract | Compound of the following general formula (I): R1-NH-CH (R2) -P (> = O) (OR3) -CH2-C (R4) (R5) -CONH-CH (R6) -COOR7 (I) or a pharmaceutically acceptable salt thereof, for which: - R1 represents a group -C (> = O) -OC (R8) (R9) -OC (> = O) -R10, in which - R8 and R9 represent, independently of each other, a hydrogen atom or an alkyl group, - and R10 represents an alkyl group, - R2 represents: - a linear or branched alkyl group, comprising 1 to 6 carbon atoms, - a phenyl group; - R3 represents a hydrogen atom or a group of the formula -C (R12) (R13) -OC (> = O) -R14, in which - R12 and R13 represent, independently of each other, a hydrogen atom or an alkyl group, - and R14 represents an alkyl group; - R5 represents a hydrogen atom and R4 represents: - a benzyl optionally substituted in the phenyl nucleus by: - 1 to 5 halogen atom (s) such as fluorine or bromine; - an OR15 or SR15 group, in which R15 represents a hydrogen atom, a benzyl group or a saturated or unsaturated, linear or branched hydrocarbon chain, comprising from 1 to 4 carbon atoms; - an amino group; - a CF3 group; - a phenyl group; or - a heteroaromatic ring of 5 or 6 links; - R4 and R5 together form, with the carbon that carries them: - a saturated hydrocarbon ring of 5 or 6 links; or - a piperidine ring, the nitrogen being in position 4 and possibly being substituted with: * a group -SO2-Ph; * a CF3 group; * a C1 to C4 alkyl group; * an acyl group from C1 to C4; * a phenyl or a benzyl optionally substituted by one or more halogen atom (s), a C1 to C4 alkyl group or a C1 to C4 alkoxy group; or * an aromatic heterocycle such as a pyridine or a pyrimidine, optionally substituted with a C1 to C4 alkyl group or a C1 to C4 alkoxy group; - R6 represents: - a linear or branched alkyl group, comprising from 1 to 6 carbon atoms, and possibly substituted with: - an OR16 group, in which R16 represents a hydrogen atom, - R7 represents a radical selected from the group consisting of a hydrogen atom, a benzyl, a C2 to C4 alkyl, -CHR18-COOR19, -CHR18-OC (> = O) R19 and -CHR18-OC (> = O) OR19, in which R18 and R19 represent, independently of each other, an alkyl, aryl, arylalkyl, cycloalkyl, cycloheteroalkyl, heteroalkyl, heteroaryl or heteroarylalkyl group. |
| priorityDate | 2008-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 293.