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filingDate 2007-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2015-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-2533264-T3
titleOfInvention Telomerase and gemcitabine inhibitor combined for cancer treatment
abstract The use of a telomerase inhibitor in the preparation of a medicament to inhibit the proliferation of cancer cells in a subject that is being treated either sequentially or simultaneously with gemcitabine, where the telomerase inhibitor comprises an oligonucleotide characterized by: (i ) N3 '→ P5' thiophosphoramidate type nucleoside junctions; (ii) have the sequence identified as SEQ ID NO: 12 and (iii) a palmitoyl moiety (C16) attached to the 5 'end of the oligonucleotide via a glycerol or aminoglycerol type linker.
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