http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2530292-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9cce74ae91129e276612f5855529149a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-25 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-80 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-25 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-80 |
| filingDate | 2014-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_53ccca7c1ba226e97d08b546c1a45abd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c86d36b01da4794e3b6036a1d1a6e3f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b5a7051f0203ddc541b37ce849f4722 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6248a56650fac64e9d4f135a90364112 |
| publicationDate | 2015-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2530292-B2 |
| titleOfInvention | Gene construction and methods to detect antifungal and antitumor compounds |
| abstract | Gene construction and methods for detecting antifungal and antitumor compounds. # The present invention relates to a gene construct for amplifying the response to signals that activate the cellular integrity pathway (CWI) in Saccharomyces cerevisiae. It comprises a hyperactive allele of the MAPKK of this route, under the control of the promoter of a gene inducible by Rlm1, which involves the creation of a positive feedback circuit whose stimulation leads to cell death. The invention also relates to methods for detecting agents that alter the cell wall or the function of components of the route itself, which allows the detection of antifungal and / or antitumor drug compounds. |
| priorityDate | 2014-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 50.