| abstract |
Compounds of formula I where R, R ', respectively independently of each other, represent A, OA, Hal, NO2 or COOA, R1, R1', respectively independently of each other, represent H, A , F, Cl, NH2, OH, CN or COOA, R1 "represents H or NH2, R2, R2 ', respectively independently of each other, represent H, Hal, A, OH, OA, CN, NO2, NR4R4 ', CH2NR4R4', O (CH2) mNR4R4 ', O (CH2) mOR4, NH (CH2) mNR4R4', O (C> = O) (CH2) mNR4R4 ', NH (C> = O) (CH2) mNR4R4' , CH2O (CH2) mNR4R4 ', CH2OR4, (CH2) mCOOR4, OSO2A, OHet, O (CH2) mCONR4R4', O (CH2) mAr, O (CH2) mCH (OH) (CH2) mOH or OSO2NR4R4 ', R2 and R2 'together represent -CH> = CH-CH> = CH-, R2 "represents H, A, Hal, OH or OA, R3, R3', respectively independently of each other, represent A, OA , Hal, NO2 or COOA, R4, R4 ', respectively independently of each other, represent H or A, A represents unbranched or branched alkyl with 1, 2, 3, 4, 5 or 6 C atoms, in where 1-5 H atoms can be r replaced by F, Het represents tetrahydrofuranyl, tetrahydropyranyl, dioxolanyl, pyrrolidinyl, piperidinyl, morpholinyl or piperazinyl, which can also be mono-substituted by> = O (carbonyl oxygen), Ar represents phenyl, Hal represents F, Cl, Br or I, m represents 1, 2 or 3, n represents 0, 1 or 2, as well as its pharmaceutically usable salts, solvates and stereoisomers, including mixtures thereof in any proportion. |