Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7c3abccac7bae9414dc8ce09b2d192dc |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-16 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C403-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-5442 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C403-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-54 |
filingDate |
2007-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2015-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae28856c376df80cfbbca7b64b271c96 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d15831115c3cbbcc494b786b9006e20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_82c1ca6d81eb10bc252e6844afed03e4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97f639afbe3eeb9185605a578dffe5e3 |
publicationDate |
2015-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
ES-2529146-T3 |
titleOfInvention |
Improved method of producing 9-cis-retinoic acid |
abstract |
Improved method of producing 9- (Z) -retinoic acid, characterized in that: a) a linear, branched or cyclic C1-C10 alkyl or phenyl ester of β-formyl-crotonic acid is reacted by the Wittig reaction with a salt of 9- (Z) -triarylphosphonium C15 in isolated form in the presence of a base to the corresponding ester of 9- (Z) -retinoic acid and b) after the end of the Wittig reaction, the reaction mixture was then saponified with a base to the corresponding carboxylate of 9- (Z) -retinoic acid and then, following protonation with an acid, the desired 9- (Z) -retinoic acid is obtained. |
priorityDate |
2006-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |