http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2528269-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_540eec52930b35c22108814088f97cb9 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D519-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2011-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3bf75d3103cd4777e7bafc98ba7d881d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7642331f82aa8e9bc7555104c96d81f8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ce99f368ab758add71d22906521fe453 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_18e4ef12279f4b6cbf1d4c76beb8ec1e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_346670cb338d1146286782be32b527b7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11ac4904a5ef4ea5a558dd727a8bd023 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7bc9318bd128a3e675ce0d95811057ef http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ff22d259095f1bd578ad5ce000763d4f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_69b74d654a58bea5644e89c87aa39be2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_05d0a8071499949ca5d6bcf52407cbc3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f02a202915b58df1ebd9ca2840726b5 |
| publicationDate | 2015-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2528269-T3 |
| titleOfInvention | Azaindazoles |
| abstract | A compound of formula (I): ** Formula ** where X and Z are independently selected from the group consisting of hydrogen, (C1-C8) alkyl, (C2-C8) alkenyl, (C2-C8) alkynyl , unsubstituted or substituted, (C3-C8) cycloalkyl, unsubstituted or substituted, (C5-C8) unsubstituted or substituted cycloalkenyl (C5-C8) -alkyl (C5-C8), unsubstituted or substituted, cycloalkenyl (C5-C8) -substituted or unsubstituted or substituted (C6-C10) bicycloalkyl, unsubstituted or substituted heterocycloalkyl, (C1-C8) -cycloalkyl-alkyl or -alkenyl ( C2-C8) unsubstituted or substituted, aryl unsubstituted or substituted, aryl (C1-C8) alkyl or -alkenyl (C2-C8) unsubstituted or substituted, heteroaryl unsubstituted or substituted, heteroarylalkyl (C1-C8) or -alkenyl (C2-C8) unsubstituted or substituted, halo, cyano, -CORa, - CO2Ra, -CONRaRb, -CONRaNRaRb, -SRa, -SORa, -SO2Ra, -SO2NRaRb, nitro, -NRaRb, -NRaC (O) Rb, -NRaC (O) NRaRb, -NRaC (O) ORa, -NRaSO2Rb, - NRaSO2NRaRb, -NRaNRaRb, -NRaNR aC (O) Rb, -NRaNRaC (O) NRaRb, -NRaNRaC (O) ORa, -ORa, -OC (O) Ra, and - OC (O) NRaRb; Y is H or halo; R1 is (C1-C8) alkyl, (C2-C8) alkenyl, (C2-C8) alkynyl, unsubstituted or substituted (C3-C8) cycloalkyl, (C3-C8) -cycloalkyl (C1-C8) -alkyl or -alkenyl Unsubstituted or substituted (C2-C8), unsubstituted or substituted (C5-C8) cycloalkenyl, (C5-C8) -cycloalkenyl (C1-C8) -alkyl or unsubstituted or substituted -C2-C8-alkenyl, (C6-cycloalkyl) -C10), unsubstituted or substituted heterocycloalkyl, heterocycloalkyl (C 1 -C 8) -alkyl or unsubstituted or substituted-C 2 -C 8 -alkenyl, unsubstituted or substituted aryl, aryl-C 1 -C 8 -alkyl or -C 2 -alkenyl -C8) unsubstituted or substituted, unsubstituted or substituted heteroaryl, heteroaryl-C1-C8-alkyl or unsubstituted or substituted -C2-C8-alkenyl, -CORa, -CO2Ra, - CONRaRb, -CONRaNRaRb; R3 is hydrogen, (C1-C8) alkyl, cyano, trifluoromethyl, -NRaRb, or halo; R6 is selected from the group consisting of hydrogen, halo, (C1-C8) alkyl, (C2-C8) alkenyl, (C2-C8) alkynyl, unsubstituted or substituted cycloalkyl, (C3-C8) cycloalkyl -substituted or unsubstituted (C1-C8) alkyl, unsubstituted or substituted (C5-C8) cycloalkenyl, unsubstituted or substituted (C1-C8) cycloalkenyl, (C6-C10) bicycloalkyl, non-heterocycloalkyl substituted or substituted, unsubstituted or substituted heterocycloalkyl-alkyl (C1-C8), unsubstituted or substituted aryl, unsubstituted or substituted aryl-C1-C8), unsubstituted or substituted heteroaryl, heteroaryl-C1-C8 alkyl unsubstituted or substituted, cyano, -CORa, -CO2Ra, -CONRaRb, -CONRaNRaRb, - SRa, -SORa, -SO2Ra, -SO2NRaRb, nitro, -NRaRb, -NRaC (O) Rb, -NRaC (O) NRaRb, -NRaC (O) ORa, -NRaSO2Rb, - NRaSO2NRaRb, -NRaNRaRb, -NRaNRaC (O) Rb, -NRaNRaC (O) NRaRb, -NRaNRaC (O) ORa, -ORa, -OC (O) Ra, - O) NRaRb; wherein any (C1-C8) alkyl, (C2-C8) alkenyl, (C2-C8) alkynyl, cycloalkyl, cycloalkenyl, bicycloalkyl, heterocycloalkyl, aryl, or heteroaryl group is optionally substituted by 1, 2 or 3 groups selected independently of the group consisting of halo, (C1-C6) alkyl, (C3-C8) cycloalkyl, (C5-C8) cycloalkenyl, halo (C1-C6) alkyl, cyano, -CORa, -CO2Ra, -CONRaRb, -SRa, -SORa , -SO2 a, -SO2NRaRb, nitro, -NRaRb, -NRaC (O) Rb, - NRaC (O) NRaRb, -NRaC (O) ORa, -NRaSO2Rb, -NRaSO2NRaRb, -ORa, -OC (O) Ra, -OC (O) NRaRb, heterocycloalkyl, aryl, heteroaryl, aryl-C1-C4-alkyl, and heteroaryl-C1-C4-alkyl; wherein any aryl or heteroaryl moiety of said aryl, heteroaryl, aryl-C1-C4-alkyl, or heteroaryl-C1-C4-alkyl is optionally substituted by 1, 2, or 3 groups selected independently from the group consisting of halo , (C1-C6) alkyl, (C3-C8) cycloalkyl, (C5-C8) cycloalkenyl, (C1-C6) haloalkyl, cyano, -CORa, -CO2Ra, -CONRaRb, - SRa, -SORa, -SO2Ra, - SO2NRaRb, nitro, -NRaRb, -NRaC (O) Rb, -NRaC (O) NRaRb, -NRaC (O) ORa, -NRaSO2Rb, - NRaSO2NRaRb, -ORa, -OC (O) Ra, and -OC (O) NRaRb; and Ra and Rb are each independently hydrogen, (C1-C8) alkyl, (C2-C8) alkenyl, (C2-C8) alkynyl, (C3-C8) cycloalkyl, (C5-C8) cycloalkenyl, (C6-C10) cycloalkyl ), heterocycloalkyl, aryl, heteroaryl, wherein said (C1-C8) alkyl, (C2-C8) alkenyl, (C2-C8) alkynyl, cycloalkenyl, bicycloalkyl, heterocycloalkyl, aryl or heteroaryl group is optionally substituted with 1, 2 or 3 groups independently selected from halo, hydroxyl, (C1-C4) alkoxy, amino, (C1-C4) -alkyl-amino, ((C1-C4) -alkyl) ((C1-C4) -alkyl) amino, -CO2H, -CO2-C1-C4-alkyl, -CONH2, -CONH-C1-C4-alkyl, -CON (C1-C4-alkyl) (C1-C4-alkyl), -SO2-C1-C4-alkyl ), -SO2NH2, -SO2NH (C1-C4) alkyl, and -SO2N (C1-C4 alkyl) ((C1-C4) alkyl); or Ra and Rb taken together with the nitrogen to which they are attached represent a 5-8 membered saturated or unsaturated ring, optionally containing an additional heteroatom selected from oxygen, nitrogen and sulfur, wherein said ring is optionally substituted by 1,2 or 3 groups independently selected from (C1-C4) alkyl, (C1-C4) haloalkyl, amino, (C1-C4) -alkyl-amino, ((C1-C4) -alkyl) ((C1-C4) -alkyl) amino, hydroxyl , oxo, (C1-C4) alkoxy, and (C1-C4) alkoxy-(C1-C4) alkyl, wherein said ring is optionally fused to a (C3-C8) cycloalkyl, heterocycloalkyl, aryl, or heteroaryl ring; or Ra and Rb taken together with the nitrogen to which they are attached represent a 6 to 10 membered bridged bicyclic ring system optionally fused to a (C3-C8) cycloalkyl, heterocycloalkyl, aryl or heteroaryl ring; or one of its pharmaceutically acceptable salts. |
| priorityDate | 2010-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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Total number of triples: 1393.