abstract |
A compound represented by the structure of formula VI: ** Formula ** wherein R1 ', R3', R4 ', R6', R7 'and R9' are the same and are selected from heterocycloalkyl, alkoxy and dialkylamino and R10 is methyl ; or by the structure of formula XIV: ** Formula ** or by the structure of formula XV: ** Formula ** or by the structure of formula XVI: ** Formula ** for use in treatment in a subject of diseases that can be treated by stimulating or increasing the expression and / or activity of telomerase and selected from a neurodegenerative disease, nervous system injury, vascular disease, a disease or disorder associated with aging, a degenerative disease of the joints, a degenerative disease of the skeletal system, a degenerative disease of the musculature, macular degeneration, infection, deterioration of the immune system, cancer, degenerative inflammatory disease, a genetic disorder that causes accelerated cell renewal, anemia, male or female infertility and a acute or chronic disease or skin disorder by contact of the affected skin with the compound. |