http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2525811-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5e56616766a93e5247ecc15446aee157 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_73f5e16a663035df37ee4d9409e2514e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-085 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 |
| filingDate | 2009-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_30d49670d2573ac43874f7caed899af5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5fd574d9e01e3764e829f97a162d0fad http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51dde9515ec2a2f7da7f1c1861cdefe2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_091180ed44bd6edf52032c36db271461 |
| publicationDate | 2014-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2525811-T3 |
| titleOfInvention | Pharmaceutical composition containing angiotensin (1-9) for cardiovascular, pulmonary and / or cerebral treatment |
| abstract | The present invention relates to a pharmaceutical composition comprising an effective amount of angiotensin- (1-9) or its derivatives and at least one pharmaceutically acceptable carrier, excipient, stabilizer, diluent and / or adjuvant. In addition, the present invention describes the use of the pharmaceutical composition and the angiotensin- (1-9) peptide or peptides derived therefrom that are biological or chemical analogs for the preparation of medicaments useful for preventing, reversing, inhibiting and / or decreasing cardiovascular remodeling. , pulmonary, cerebral or renal. In addition, this invention also comprises a method for preventing, reversing, inhibiting and / or decreasing cardiovascular, pulmonary, cerebral or renal remodeling, which consists of raising the concentration in blood and / or tissues of the angiotensin- (1-9) peptide or its derivatives by means of a pharmaceutical composition containing a vector that expresses ECA2, an enzyme responsible for the endogenous production of angiotensin- (1-9). These vectors correspond to adenovirus, retrovirus, lentivirus or adeno-associated virus that contains the gene that codes for ECA2. This invention allows the administration of angiotensin- (1-9) or its derivatives orally, for injection, continuous infusion by pump, or raising its levels in the body by treatment with angiotensin-I converting enzyme inhibitors, with antagonists of the angiotensin II receptor (ARA II), with Rho kinase inhibitors, with calcium L channel antagonists and / or with diuretics. |
| priorityDate | 2008-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
| Predicate | Subject |
|---|---|
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID5460341 http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419559505 |
Total number of triples: 21.