http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2525545-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_558514e7c79e7c262491474fff0ba6b8 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16H10-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A90-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-112 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57484 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5091 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2006-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e166bbc8526aad55784e8370b5818f60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86c54b4478a626fe83aea9817aaa0059 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1fbaf93ba115751a32c14509c1060180 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1365fff23a61933b8fdf1666ee3a4a20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e69e255af0dc38fd0670c94284c7d151 |
| publicationDate | 2014-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2525545-T3 |
| titleOfInvention | Methods and uses to identify the origin of a carcinoma of unknown primary origin |
| abstract | A method of identifying the origin of a metastasis of unknown origin that comprises the steps of a. Measure the Biomarkers associated with at least six different carcinomas in a sample containing metastatic cells where the Biomarkers are expression levels of at least the following Marker genes: SP-B, TTF1, DSG3, PSCA, F5, HPT1, PSA, MGB / MG, WT1 and PDEF; b. combine the data of the Biomarkers in an algorithm where the algorithm i. Normalize the Biomarkers against the reference; and ii. imposes a cut-off point that optimizes the sensitivity and specificity of each Biomarker, weighs the prevalence of carcinomas and selects a tissue of origin; C. determine the origin based on the highest probability determined by the algorithm or determine that the carcinoma is not derived from a particular set of carcinomas; and d. optionally measure specific Biomarkers for one or more additional different carcinomas, and repeat steps c) and d) for additional Biomarkers. |
| priorityDate | 2005-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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