http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2525179-T3
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_28e3113097dd6d28720572e47f2f2407 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-02 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-02 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-04 |
filingDate | 2010-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2014-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9e0f670ae3e1ce4eab489a822112aaa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c830df528a6c691a9de3d87a0940e9a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_80177a68ece32dc6c371df95e9af6f30 |
publicationDate | 2014-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-2525179-T3 |
titleOfInvention | U neuromedin derivative |
abstract | A compound represented by the formula ** Formula ** [wherein Y represents a polypeptide consisting of an amino acid sequence presented in SEQ ID No. 1, where 1 to 4 amino acids are substituted, the amino acid substitution is select from: (1) substitution of the Tyr from position 1 with Arg, Phe, NMeTyr or Pro; (2) Phe substitution of position 2 with Glu, Tyr, Trp or Nal (2); (3) replacement of Leu from position 3 with Gln, Arg, Val, Cha or NMeLeu; (4) Phe substitution of position 4 with Trp; (5) replacement of the Arg from position 5 with Gln or NMeArg; (6) replacement of Pro from position 6 with Ala or NMeAla; and (7) replacement of the Arg from position 7 with Arg (Me) or NMeArg; X represents a methoxypolyethylene glycol; X 'is absent or represents a methoxypolyethylene glycol; The is a divalent or trivalent group represented by the formula ** Formula ** or (where R represents a bond and n is an integer of 0); Lb represents - (CH2) i- (where i is an integer from 1 to 5); Lc is a divalent group represented by the formula (i): -NH-Qc-Cb- [where Qc is a divalent group represented by the formula: - (CH2) m1- (where m1 is an integer from 0 to 15 ), and Cb represents a bond, -CO- or -SO2-), or a divalent group represented by the formula (ii): -Qc'-Cb'- [wherein Qc 'is a divalent group represented by the formula: - (CH2) m1'-Zc '- (CH2) m2'- (where m1' is an integer from 0 to 15, Zc 'represents ** Formula ** and m2' is an integer from 0 to 15), and Cb 'represents a -CO- or -SO2-] bond; and j is an integer from 1 to 3]; or a salt thereof. |
priorityDate | 2009-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 829.