http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2524888-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e0bf0928b608797b70bbc2b91c7e52e |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-14 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C209-26 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-08 |
| filingDate | 2011-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2895238bf7d4e60cb6cb361adf8c6d93 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be545d73c46991665d0e58b97a0b29f2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6a9f593c8641819f0e87b33f92712013 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a492d450ee4c79630f169a91332263f0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd81e22ea2b21f21d696c99ef527df39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cdde3e7cddf25b8259e57f9efad240d3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86920592bc70c05c56f498a32485d4cf |
| publicationDate | 2014-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2524888-T3 |
| titleOfInvention | Procedure for the preparation of asymmetric secondary tert-butylamines in liquid phase |
| abstract | Process for the preparation of asymmetric secondary tert-butylamines of formula I by reductive amination of aldehydes of formula II with tert-butylamine and hydrogen in liquid phase in the presence of hydrogenation catalysts, comprising the following steps: (i) providing tert-butylamine and the hydrogenation catalyst in a pressure vessel, (ii) adding hydrogen and continuously adding an aldehyde of formula II R-CHO II, wherein the aldehyde of formula II is selected from the group of acetaldehyde, propionaldehyde, n-butyraldehyde, ibutiraldehyde, secondary butyraldehyde, pivalaldehyde, n-pentanal, n-hexanal, 2-ethylhexanal, 2-methylpentanal, 3- methylpentanal, 4-methylpentanal, n-octanal, n-decanal, n-undecanal, n-dodecanal, 11-methyldodecanal , cyclopentyl aldehyde, cyclohexylaldehyde, cycloheptylaldehyde, adamantyl aldehyde, phenylacetaldehyde and benzaldehyde or mixtures of these aldehydes and the proportion with respect to hydrogen and aldehyde of formula II is at least equimolar, (iii) maintaining the temperature during the addition of the aldehyde in step (ii) in the range of 50 to 150 ° C and maintaining the total pressure during the addition of the aldehyde in step (ii) in the range of 200 to 12,000 kPa, (iv) dehydrate the hydrogenation discharge from step (iii), which contains the secondary tert-butylamine of formula I formed ** Form ** and the reaction water and (v) distill fractionally then the dehydrated hydrogenation discharge of step (iv) and in which steps (i) to (iii) are carried out in the presence of an inert solvent under the reaction conditions or none. |
| priorityDate | 2010-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 115.