| abstract |
A stabilized HSA-free pharmaceutical composition basically comprising monomeric interferon-beta (IFN-ß) or a variant thereof solubilized in a low ionic strength formulation, wherein said low ionic strength formulation is a solution comprising a buffer in an amount sufficient to maintain the pH of said composition above or below 0.5 units of a specified pH of 3.0 or 5.0, said formulation has an ionic strength of less than 60 mM, and in which IFN-ß is covalently bonded with polyethylene glycol |