| abstract |
Pharmaceutical controlled release composition for oral use consisting of dimethyl fumarate as an active ingredient, in which the daily dosage is from 480 to 720 mg of active ingredient administered in one to three doses, in which the composition is for use in the treatment of an autoimmune disease, in which the autoimmune disease is selected from: i. polyarthritis ii. multiple sclerosis (MS) iii. juvenile onset diabetes mellitus iv. Hashimoto's thyroiditis v. Grave's disease vi. SLE (systemic lupus erythematosus) vii. Sjogren's syndrome viii. pernicious anemia ix. chronic active hepatitis (lupoid) x. rheumatoid arthritis (RA) xi. optic neuritis |