| abstract |
A conjugate of general formula (I) or a pharmaceutically acceptable salt thereof: wherein, ** Formula ** R is selected from linear or branched C1-4 alkyl, preferably methyl or ethyl, more preferably methyl; R1 and R2 are each independently selected from hydrogen or linear or branched C1-4 alkyl; preferably hydrogen, methyl or ethyl; X is chosen from O, S, NH, ** Formula ** I is an integer chosen from 1-20, preferably from 1-10, more preferably from 1-5; m is an integer chosen from 50-20000, preferably from 100-1000; n is an integer chosen from 1-20, preferably from 1-10, more preferably from 1-5; The G-CSF is chosen from among the natural G-CSF, the recombinant G-CSF or the product of a gene mutation having the function of the G-CSF. |