| abstract |
A compound of formula (I): ** Formula ** or one of its salts or solvates, wherein R1 is - (Q1) x-R5; Q1 is C1-C6 alkylene; x is 0 or 1; R5 is -CF3 or cyclopropyl; R2 is - (Q3) - (Q4) -R6 or - (Q3) -CN; Q3 is C1-C6 alkylene; Q4 is -C (O) -, -C (S) - or -C (NR7) -, R7 is H or C1-C6 alkyl; R6 is C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, hydroxy, C1-C6 alkoxy, phenoxy, benzyloxy or -N (R8) (R9) R8 and R9 are each independently H, hydroxy, C1- alkyl C6, C2-C6 alkenyl, C2-C6 alkynyl, - (Q5) and cycloalkyl (C3-C6), -N (R10) (R11) or R8 and R9 combine with the nitrogen atom to which they are bound to form a optionally substituted 4- to 8-membered ring that may contain additional heteroatoms and may contain one or more degrees of unsaturation; Q5 is C1-C6 alkylene; y is 0 or 1; R10 and R11 are each independently H or C1-C6 alkyl; R3 is -CN, -NO2 or halogen; and R4 is -CN, -NO2, halogen, C1-C6 haloalkyl, C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, hydroxy, C1-C6 alkoxy, phenyl, naphthyl, phenoxy or benzyloxy .. |