abstract |
An oral pharmaceutical composition, in the form of a solid tablet, comprising an active ingredient and 0.1% to 60% by weight of at least one cyclodextrin agent, as an excipient, with respect to the total weight of the composition; the active ingredient being a 2-oxo-1-pyrrolidine derivative of formulas (I), ** Formula ** wherein, R 1 is C 1-10 alkyl or C 2-6 alkenyl; R2 is C1-10 alkyl or C2-6 alkenyl; X is -CONR4R5, -COOH, -COOR3 or -CN; R3 is C1-10 alkyl; R4 is hydrogen or C1-10 alkyl; R5 is hydrogen or C1-10 alkyl. |