http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2516691-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ca2e4410855da087e11bf3eea8933fa |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D257-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D257-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 |
| filingDate | 2006-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d6272343fe195d6395c3ab42126d0915 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2012aae8b8756125ba3ae2063cdcaee4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_72045d20a99e7e448259d7bc8d95c497 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd957b09deaef13fcba6fc012ed26d48 |
| publicationDate | 2014-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2516691-T3 |
| titleOfInvention | Glucagon receptor antagonists, preparation and therapeutic uses |
| abstract | A compound structurally represented by Formula I ** Formula ** or a pharmaceutically acceptable salt thereof, wherein: M is -CH2- or a bond; R1 and R2 are independently -H or -halogen; R3 is -C1-C8-alkyl (optionally substituted with 1 to 3 halogens), -C3-C7-cycloalkyl, -C1-C6-alkyl-C3-C7-cycloalkyl-C3-C7-alkyl (C1-C6) (optionally substituted with 1 to 3 halogens); R4 and R5 are independently -H, -halogen, -hydroxy, -hydroxymethyl, -CN, -C1-C7-alkoxy, -C2-C7-alkenyl, or -C1-C6-alkyl (optionally substituted with 1 to 3 halogens); R6 is ** Formula ** in which the zigzag line shows the point of attachment to the precursor molecule; R7 and R8 are independently -H, -halogen, -C1-C6-alkyl (optionally substituted with 1 to 3 halogens), -C1-C6-alkoxy, -C3-C7-cycloalkyl, -C (O) R10, -COOR10, -OC (O) R10, -OS (O) 2R10, -SR10, - S (O) R10, -S (O) 2R10 or -O-alkenyl (C2-C7); R9 is independently -H, -halogen, -CN, -C3-C7-cycloalkyl, -C (O) R10, -COOR10, -OC (O) R10, - OS (O) 2R10, -SR10, -S ( O) R10, -S (O) 2R10, or -O-alkenyl (C2-C7), -alkoxy (C1-C3) (optionally substituted with 1 to 3 halogens) or -C1-C6 alkyl (optionally substituted with 1 to 3 halogens); and R10 is independently in each occurrence -hydrogen or-(C1-C6) alkyl (optionally substituted with 1 to 3 halogens). |
| priorityDate | 2005-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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