http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2514471-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c4180fc57a693864e2ce2dbfd64a9278 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 |
| filingDate | 2006-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3f332530c03c4a60bb6ded70f607fa1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6230eee6f3ab84e605c49c281291d270 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bddc5b9fc6abe25edf60fb083a32c9a6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_837b5023562fdfac10a90c0e0c632809 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b5d478df62de9bee2290c64cc3c94ad http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6a82ebbc65235ebc130bdeca6e7b9eae http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c2cefa82c86a98294d046e5bca0553c6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a55255df78e54bee0b607f63fe597e5f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c97f1c34354f9ac1b6c80e06775919c5 |
| publicationDate | 2014-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2514471-T3 |
| titleOfInvention | Pyrimidin-amide compounds as PGDS inhibitors |
| abstract | A compound of formula (I): ** Formula ** where: R1 is phenyl optionally substituted with halogen, (C1-C6) alkyl, hydroxy, (C1-C6) alkoxy, halogeno (C1-C4) alkyl or halogenoalkoxy (C1- C4); R2 is hydrogen or (C1-C4) alkyl; R3 is phenyl, pyridyl, thiazolyl, imidazolyl, oxodiazolyl, imidazolyl, pyrimidinyl, thiophenyl, oxazolyl, cycloalkyl, 1,2,4-thiadiazolyl, 1,3,4-thiadiazolyl, tetrahydropyranyl, piperidinyl, furanyl, benzo [1,3] dioxolyl, imidazolidinyl or 1,3-dihydro10 benzo [c] isothiazolyl, each of which is optionally substituted with: acyl, cyano, nitro, halogen, hydroxy, carboxy, amidino, R5O-C (> = O) -C ( > = N-OR4) -, Y1Y2N-, Y1Y2N-C (> = O) -, Y1Y2N-C (> = O) -O-, Y1Y2N-SO2-, R7-SO2-NR6-, R7-C (> = O) -NR6-, Y1Y2N-alkylene- (C1-C4) -SO2-alkylene- (C1-C4) -, or alkyl, alkenyl, alkynyl, alkoxy, alkoxycarbonyl, alkylthio, alkylsulfinyl or alkylsulfonyl, each of which it is optionally substituted with: halogen, alkoxy, halogenoalkoxy, hydroxy, carboxy, alkoxycarbonyl, -P (> = O) - (alkoxy) 2, Y1Y2N-, Y1Y2NSO2-, R7-SO2-NR6-, aryl or heteroaryl, each of which is optionally substituted with alkyl, halogen, halogenoalkyl, alkoxy, halogenoalkoxy, hydroxy, amino, alkyl ilamino, dialkylamino, carboxy, or alkoxycarbonyl, or heterocyclyl or arylheterocyclyl, each of which is optionally substituted with oxo or alkyl, or aryl, heteroaryl, aroyl, heteroaroyl, aryloxy, heteroaryloxy, or heterocyclyl, each of which is optionally substituted with alkyl, halogenoalkyl, halogen, alkoxy, halogenoalkoxy, hydroxy, carboxy, alkoxycarbonyl, -P (> = O) - (alkoxy) 2, Y1Y2N-, or Y1Y2N-SO2-, and when R3 is cycloalkyl, tetrahydropyranyl, piperidinyl, imidazolidinyl, or 1,3-dihydrobenzo [c] isothiazolyl, is also optionally substituted with oxo; L1 is a bond, or (C1-C6) alkylene optionally substituted with hydroxy; R4, R5 and R6 are each independently hydrogen or alkyl, R7 is alkyl optionally substituted with hydroxy, halogen or alkoxy, or aryl, heteroaryl, arylalkyl or heteroarylalkyl, wherein the aryl, heteroaryl or aryl or heteroaryl moiety of the arylalkyl or heteroarylalkyl it is optionally substituted with alkyl, halogenoalkyl, hydroxy, carboxy, alkoxycarbonyl, amino, alkylamino, dialkylamino, halogen, alkoxy or halogenoalkoxy; and each of Y1 and Y2 is independently: hydrogen, alkyl optionally substituted with: hydroxy, carboxy, halogen, amino, alkylamino, dialkylamino, cycloalkylamino, aminocarbonyl, alkylaminocarbonyl, dialkylaminocarbonyl, cycloalkylaminocarbonyl, alkoxy optionally substituted with hydroxy, cycloalkyl, heterocyclyl, aryl or heteroaryl, each of which is optionally substituted with alkyl, halogen or halogenoalkyl. |
| priorityDate | 2005-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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Total number of triples: 682.