http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2493916-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5ec699c96c809fdf202410d55b5cd797 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F5-025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N55-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-47 |
| filingDate | 2010-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f23429b974fbcf03cf11a072ebf96eb1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b75d9de8c7b3614d858edeab7245e21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e663c4c0dfdc0bd995465530c1329e40 |
| publicationDate | 2014-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2493916-T3 |
| titleOfInvention | Inhibitors of fatty acid amide hydrolase |
| abstract | Compound of formula I: or a pharmaceutically acceptable salt, or solvate thereof, or mixture thereof, in which: ----- is selected from a single bond and a double bond; when ----- is a single bond, X1 is selected from CR4R5 and NR6, and X2 is selected from CR7R8 and NR9; when ----- is a double bond, X1 is selected from CR4 and N, and X2 is selected from CR7 and N; X3 is selected from CR10R11 and NR12; with the proviso that at least one of X1, X2 and X3 is selected from N, NR6, NR9, and N12; m is 0 or 1; Z1 is selected from -OR13 and C1-6 alkyl; Z2 is selected from -OR14 and C1-6 alkyl; or alternatively, Z1 and Z2, together with the B to which they are attached, form a 5-8 membered ring having at least one O atom attached directly to B, in which the ring is composed of carbon atoms and optionally one or more additional heteroatoms independently selected from the group consisting of N, S, and O; n is 0, 1, 2, or 3; R1 and R2 are each independently selected from H, halogen, C1-6alkyl, C2-6alkenyl, C2-6alkynyl, perhaloC1-6alkyl, -CN and -OR15; or alternatively, R1 and R2, taken together with the carbon to which they are attached, form a carbonyl group; R3, at each occurrence, is independently selected from halogen, C1-6alkyl, C2-6alkenyl, C2-6alkynyl, perhaloC1-6alkyl, -OH, C1-6alkoxy and -CN; R4, R5, R7, R8, R10, and R11 are each independently selected from H, halogen, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C1-6 perhaloalkyl, -CN, -OR16, NR17R18, -C (O) R19, C3-10 carbocyclyl, C6-10 aryl, C7-12 aralkyl, 3-10 membered heterocyclyl, and 5-10 membered heteroaryl; R6, R9, and R12 are each independently selected from H, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, - C (O) R20, S (O) 2R22, C3-10 carbocyclyl, C6- aryl 10, 3-10 membered heterocyclyl, 5-10 membered heteroaryl, and - (CR27R28) p-R23; R13 and R14, at each occurrence, are each independently selected from H, C1-6 alkyl, C2-6 alkenyl, and C2-6 alkynyl; R15 and R16, at each occurrence, are each independently selected from H, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C3-10 carbocyclyl, C6-10 aryl, C7-12 aralkyl, 3- heterocyclyl 10 members, and 5-10 membered heteroaryl; R17 and R18, at each occurrence, are each independently selected from H, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, -C (O) R24, -C (O) OR25, C3-10 carbocyclyl, C6-10 aryl, C7-12 aralkyl, 3-10 membered heterocyclyl, and 5-10 membered heteroaryl; |
| priorityDate | 2009-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 44.