http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2488668-T3
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_606fd60f22dd25c2d7dd7b2a0480597b |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-03 |
filingDate | 2008-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2014-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c78018a58a076a319793d9ac81b928f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e11370892b3d33ebdfab0b062af2202a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f07670c0e10f2898de855df49b279c6e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c18cd88a258e86407bac8aca4bc07dc0 |
publicationDate | 2014-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-2488668-T3 |
titleOfInvention | Aprotinin-like polypeptides for administering agents conjugated therewith to tissues |
abstract | Polypeptide comprising an amino acid sequence having the following formula: X1-X2-X3-X4-X5-X6-X7-X8-X9-X10-X11-X12-X13-X14-X15-X16-X17-X18-X19 where X1-X19 are any amino acid or are absent; at least one of X10 and X15 is Arg; and said amino acid sequence is at least 80% identical to Angiopep-7, which has the amino acid sequence of SEQ ID NO: 112; wherein said polypeptide is efficiently transported to at least one cell or tissue selected from the group consisting of liver, lung, and kidney, and wherein said polypeptide is transported across the blood-brain barrier at levels below Angiopep- 6, which has the amino acid sequence of SEQ ID NO: 111. |
priorityDate | 2007-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1409.