http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2485389-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1224e3c07b7cc5684ee81d9e1e5ee15c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C231-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C237-46 |
| filingDate | 2009-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_24f55732a2637230b8c5df61cd0af951 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d161481bfe4552585b551b644e15673 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_213e4e0404f539a3e720db520c89b94f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6bd1f5ba60eda75f67fa357113855b54 |
| publicationDate | 2014-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2485389-T3 |
| titleOfInvention | Synthesis of iodixanol in propylene glycol |
| abstract | A process for the dimerization of 5-acetamido-N, N'-bis (2,3-dihydroxypropyl) -2,4,6-triiodo-isophthalamide (compound A) in a temperature range of 10 to 20 ° C using propylene glycol as solvent in a concentration of 0.8 to 1.3 ml of solvent per g of compound A, in the presence of 0.3 to 0.4 molar equivalents of epichlorohydrin with respect to compound A, and wherein the reaction solution it has a pH value of 11.5 to 12.0, so that the pH varies throughout the dimerization, having a higher value at the beginning of the dimerization than at the end of it. |
| priorityDate | 2009-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.