http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2483738-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_68f2bd3d611c7a2a832128d8430d9193 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-454 |
| filingDate | 2009-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_98157eea5e3b525c7f5ac0c4a6ea7351 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f0da3bc4ff7803173ef0facf2d0ff6eb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c41df4d2c64e964d5750bfba722421e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_356adf67832afa9022a5572bfd067580 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ef8a35d1524dd3efc73c0bfb708bee3 |
| publicationDate | 2014-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2483738-T3 |
| titleOfInvention | Melanocortin receptor antagonist compounds, processes to prepare them and their use in human and cosmetic medicine |
| abstract | Compounds of general formula (I) indicated below: ** Formula ** in which: R 1 represents a hydrogen atom, an aryl that is an unsubstituted phenyl or naphthyl, a substituted aryl that is a phenyl or a naphthyl substituted with one or more groups of atoms chosen from an alkyl, an alkoxy, a halogen, a hydroxyl, a cyano, a trifluoromethyl and a nitro, an alkyl, a cycloalkyl or a cycloalkylalkyl, R2 represents a hydrogen atom, a hydroxyl or a lower alkyl which is a linear or branched saturated or unsaturated hydrocarbon-based chain containing from 1 to 4 carbon atoms or an unsaturated chain containing from 2 to 4 carbon atoms, a substituted lower alkyl which is a hydrocarbon-based chain saturated or linear or branched unsaturated containing 1 to 4 carbon atoms and substituted with one or more halogen atoms or with a hydroxyl, or an unsaturated hydrocarbon-based chain containing 2 to 4 carbon atoms carbon and substituted with one or more halogen atoms or with a hydroxyl, a higher alkyl which is a saturated or unsaturated linear or branched hydrocarbon chain containing from 5 to 10 carbon atoms, a substituted higher alkyl which is a chain based in saturated or unsaturated linear or branched hydrocarbon containing from 5 to 10 carbon atoms and substituted with one or more halogen atoms or with a hydroxyl, a cycloalkyl, a cycloalkylalkyl, a lower alkoxy which is an oxygen atom substituted with an alkyl lower, a substituted lower alkoxy which is an oxygen atom substituted with a lower alkyl substituted a higher alkoxy which is an oxygen atom substituted with a higher alkyl, a substituted higher alkoxy which is an oxygen atom substituted with a substituted higher alkyl, a cycloalkylalkoxy, an acyloxy, an acyl, an alkoxycarbonyl, a carboxamide, a carboxylic acid, a cyano or an amino disusti tuido with an acyl and an aryl which is a phenyl or naphthyl or unsubstituted alkyl, R3 represents an aralkyl which is an alkyl substituted with an aryl or a substituted aralkyl which is an alkyl substituted with a substituted aryl, R4 represents a heteroaralkyl which is an alkyl substituted with heteroaryl or a substituted heteroaralkyl which is an alkyl substituted with a substituted heteroaryl, R5 represents a hydrogen atom or an alkyl, X represents an oxygen atom or a sulfur atom, n, m can be equal to 1 or 2; and in addition, the corresponding salts and enantiomers, characterized in that they have antagonistic activity with respect to the MC4R receptor. |
| priorityDate | 2008-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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