http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2483516-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2432997f9dd07522f631509ed856a31d |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D275-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D279-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D275-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5415 |
| filingDate | 2010-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_41902d50b20816520abcadea75d26e63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2645bfdf0a955ffd16e77da606133535 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ce689e0819883575f1902a7cbfedb0e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_39ca490821a88aee5034b2458826e736 |
| publicationDate | 2014-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2483516-T3 |
| titleOfInvention | Benzothiazine derivatives, their preparation and application as drugs |
| abstract | Compounds presenting the general formula (I): ** Formula ** in which: R1 represents: Hydrogen; C1-C6 alkyl; COR5; SO2R5; CO (CH2) mR6; CO (CH2) mOR6; (CH2) mR6; (CH2) mCONR7R8; (CH2) nNR7R8; (CH2) NOR6; CHR7OR9; (CH2) mR10 m represents: 1 to 6 n represents: 2 to 6 R2 represents: - a phenyl substituted with one or more groups selected from a halogen, C1-C6 alkyl, CN, OH, CF3, OCF3, SMe, COMe , CMe (OH) CF3, CH (OH) CF3, COOR7, CONR7R11; - a naphthyl, 1,2,3,4-tetrahydro-naphthalene, biphenyl, phenyl pyridine or a different indole heterocycle, in the case where R1, R4 and R'4 represent a hydrogen, either unsubstituted or substituted with one or more groups selected from a halogen or C1-C6 alkyl, CN, OH, CF3, OCF3, OMe, SMe; - a cycloalkyl, or unsubstituted or substituted with OH, CONH2, SO2Me, SO2NH2; with the proviso that: - the R2 group is always attached to the carbonyl through a carbon atom; - when R2 is a phenyl, the COOR7 substituent is never in position 4 in relation to carbonyl; R3 represents: methyl or ethyl; R4 and R'4, identical or different, represent: hydrogen; halogen; C1-C6 alkyl; CN; CF3; OCF3; SMe; OMe; NR7R8; SO2Me; R5 represents: C1-C6 alkyl; phenyl, or unsubstituted or substituted with one or more groups selected from halogen, C1-C6 alkyl, CN, OH, CF3, OCF3, SMe; a naphthyl, or unsubstituted or substituted with one or more groups selected from halogen or C1-C6 alkyl, CN, OH, CF3, OCF3, SMe; a cycloalkyl, either unsubstituted or substituted with a CONH2, SO2Me, SO2NH2; heteroaryl, or unsubstituted or substituted with one or more groups selected from halogen, C1-C6 alkyl, CN, OH, CF3, OCF3, SMe; R6 represents: hydrogen; C1-C6 alkyl; phenyl, or unsubstituted or substituted with one or more groups selected from halogen, C1-C6 alkyl, CN, OH, CF3, OCF3, SMe; a naphthyl or heterocycle, or unsubstituted or substituted with one or more groups selected from halogen or C1-C6 alkyl, CN, OH, CF3, OCF3, SMe; a cycloalkyl, or unsubstituted or substituted with CONH2, SO2Me, SO2NH2. |
| priorityDate | 2009-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 547.