| abstract |
Compound represented by the following formula (I): ** Formula ** in which R1 is hydrogen, alkyl, alkenyl, C3-8 cycloalkyl, a 5-membered or 6-membered unsaturated carbocycle, or a 5-membered or 6-membered heterocycle ; X is C, O, N or S; Y is O, NH or O-C1-4alkyl; n is an integer from 0 to 10; m is an integer from 0 to 5; R2 and R3 are independently C1-6 alkyl; R4 is C5-6 cycloalkyl or a 5-membered or 6-membered unsaturated carbocycle, or a heterocycle that may be substituted with a halogen, CF3, OR7 or NR7R8, wherein R7 and R8 are independently hydrogen or C1-6 alkyl; R5 is OH, NH2 or C5-6 cycloalkyl, a 5-membered or 6-membered unsaturated carbocycle or a heterocycle in which the cycloalkyl, carbocycle and heterocycle may be optionally substituted with a halogen, NH2, NO2, C1-6 alkoxy , C1-6alkylthio, OR7, NR7R8 or CF3; and R6 is H, C1-10 alkyl which may be substituted with hydroxy or C2-10 alkenyl, or together with R1 be -C2H2-; and pharmaceutically acceptable salts, stereoisomers, enantiomers, prodrugs, and solvates thereof. |