abstract |
A compound of formula (I), or a pharmaceutically acceptable salt, solvate or N-oxide thereof: ** Formula ** wherein R 1 represents hydrogen, halogen or C 1-6 alkyl; R2 represents halogen or C1-6 alkyl; R3 represents -CONRbRc and Rb and Rc, when considered together with the nitrogen atom to which both are attached, represent azetidin-1-yl, pyrrolidin-1-yl, piperidin-1-yl, morpholin-4-yl, thiomorpholin -4-yl, piperazin-1-yl, homopiperidin-1-yl, homomorpholin-4-yl or homo-piperazin-1-yl, and any of these groups may be optionally substituted with one or more substituents selected from alkyl C1-6, C1-6 alkoxy, hydroxy, hydroxy (C1-6) alkyl, amino (C1-6) alkyl, (amino) (hydroxy) (C1-6) alkyl, halogen, oxo, (C2-6) alkyl carbonyl, carboxy, (C2-6) alkoxycarbonyl, dialkyl (C1-6) hydrazinylcarbonyl, amino, (C1-6) amino, dialkyl (C1-6) amino, (C2-6) carbonylamino, aminocarbonylamino, aminocarbonyl, (C1-6) alkylcarbonyl, dialkyl (C1-6) aminocarbonyl, aminosulfonyl, (C1-6) sulfonyl, (C1-6) alkylcarbonylalkyl (C1-6) alkyl, (C1-6) alkyl (C1-6) alkyl - 6), carboxyalkyl (C1-6), alkoxy (C2-6) carbonylalkyl (C1-6), alkoxy (C2-6) carbonylamino and alkoxy (C2-6) carbo nilaminoalkyl (C1-6). |