| abstract |
Compounds of formula I, ** Formula ** in which R1 is C1-6 alkyl or C1-6 alkyl substituted by 1-5 substituents individually selected from amino, halogen, (C1-6 alkyl, C1-6 alkyl) N - and (C1-6 alkyl, H) N-; R2 is H, C1-6 alkyl or C1-6 alkyl substituted by 1-5 substituents individually selected from amino, halogen, halogen, C1-6 alkoxy, hydroxy, C1-6 alkoxy, (C1-6 alkyl, C1-6 alkyl) N-, (C1-6 alkyl, H) N-, nitro and C1-6 alkyl S (O) 2-; R3 is H, C1-6alkyl or C1-6alkyl substituted by 1-5 substituents individually selected from amino, halogen, halogen, C1-6alkoxy, hydroxy, C1-6alkoxy, (C1-6alkyl, C1-6alkyl) N-, (C1-6 alkyl, H) N-, nitro and C1-6 alkyl-S (O) 2-; R4 is selected from the group consisting of i) H, ii) C1-6 alkyl, iii) C1-6 alkyl substituted by 1-5 substituents individually selected from amino, halogen, halogen C1-6 alkoxy, hydroxy, C1-6 alkoxy , (C1-6 alkyl, C1-6 alkyl) N-, (C1-6 alkyl, H) N-, nitro and C1-6 alkyl-S (O) 2-, iv) heterocyclyl, and v) heterocyclyl substituted by 1 -4 substituents individually selected from amino, halogen, halo C1-6 alkoxy, halogen-C1-6 alkyl, hydroxy, hydroxyalkyl C1-6, C1-6 alkoxy, alkyl-C1-6 alkoxy, C1-6 alkyl, (C1-alkyl -6, C1-6alkyl) N-, (C1-6alkyl, H) N-, nitro and C1-6alkyl-S (O) 2-; or pharmaceutically acceptable salts thereof. |