| abstract |
Antibody or fragment thereof, which binds to the extracellular domain of a B7RP1 polypeptide, in which the polypeptide: (a) is encoded by a nucleic acid molecule comprising a nucleotide sequence encoding the extracellular domain of the polypeptide exposed in Figure 12A (SEQ ID NO: 17); or (b) comprises the extracellular domain of the mature amino acid sequence set forth in Figure 12A (SEQ ID NO: 17) in which the extracellular domain spans from any of residues 19, 20, 21, 22, 24 or 28 to residue 259 of the amino acid sequence shown in Figure 12A (SEQ ID NO: 17). |