http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2462498-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-147 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4375 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D455-03 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D455-03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4375 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 |
| filingDate | 2010-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c15e9b8b5f44d1f23eba096d1017c07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2d4354570bf3af61fdff7a19ae7e5a9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_18d9caa777f4f9baa40db94223992add http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4993a3cff4a4467f2c7201f900bd5f2d |
| publicationDate | 2014-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2462498-T3 |
| titleOfInvention | Novel Isoquinoline Derivatives |
| abstract | A compound of formula (I) wherein R1 is hydrogen, alkyl, alkenyl, phenylalkyl, pyridinylalkyl, alkylpyrazylalkyl, carboxyalkyl, alkoxycarbonylalkyl, alkylaminocarbonylalkyl or oxethylaminocarbonylalkyl; R4 is halogen or alkoxy; R5 is halogen or alkoxy; R6 is hydrogen or halogen; R7 is hydrogen or halogen; and wherein R2 and R3 are a), b) or c) a) one of R2 and R3 is hydrogen and the other is selected from alkenyl and alkynyl; b) R2 and R3 are both alkyl, alkenyl or alkynyl at the same time; c) R2 and R3 together with the carbon atom to which they are attached form cycloalkyl, cycloalkenyl, oxethyl or tetrahydropyranyl; and wherein the bond between Ca and Cb is a single bond or a double bond; or a pharmaceutically acceptable salt thereof; with the proviso that 9,10-dimethoxy-8,8-dimethyl-5,8-dihydro-6H- [1, 3] dioxolo [4, 5-g] isoquin [3, 2-a] isoquinoline; 8, 8-diethyl-9, 10-dimethoxy-5, 8-dihydro-6H- [1, 3] dioxolo [4, 5-g] isoquin [3, 2-a] isoquinoline; 8,8-diethyl-9,10-dimethoxy-5,8,13,13-tetrahydro-6H- [1, 3] dioxolo [4, 5-g] isoquin [3, 2-a] isoquinoline; 8-allyl-9,10-dimethoxy-5, 8, 13, 13a-tetrahydro-6H [1, 3] dioxolo [4, 5-g] isoquin [3, 2-a] isoquinoline; 8-allyl-9, 10-dimethoxy-5, 8-dihydro-6H- [1, 3] dioxolo [4, 5-g] isoquin [3, 2a] isoquinoline; 9,10-dimethoxy-8-pent-4-enyl-5, 8-dihydro-6H- [1, 3] dioxolo [4, 5-g] isoquin [3, 2-a] isoquinoline and 9, 10 dimethoxy- 8,8-dimethyl-5, 8, 13, 13a-tetrahydro-6H- [1, 3] dioxolo [4, 5-g] isoquin [3, 2-a] isoquinoline are excluded. |
| priorityDate | 2009-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 172.