| abstract |
A compound of formula II: ** Formula ** or a pharmaceutically acceptable salt or solvate thereof, wherein: X is NR3; R1 is OR1A, NHOH, hydrogen, or alkyl, aryl, alkylaryl, arylalkyl, heteroalkyl, heterocycle, alkylheterocycle or optionally substituted heterocycloalkyl; R2 is OR2A, C (O) OR2A, hydrogen, halogen, nitrile, or alkyl, aryl, alkylaryl, arylalkyl, heteroalkyl, heterocycle, alkylheterocycle or optionally substituted heterocycloalkyl; R3 is OR3A, NHC (O) R3A, NHSO2R3A or hydrogen; R6 is OR6A, OC (O) R6A, N (R6B) 2, NHC (O) R6B, hydrogen or halogen; R7 is OR7A, OC (O) R7A, N (R7B) 2, NHC (O) R7B, hydrogen or halogen; R8 is OR8A, OC (O) R8A, N (R8B) 2, NHC (O) R8B, hydrogen or halogen; R9 is CH2OR9A, CH2OC (O) R9A, N (R9B) 2, NHC (O) R9B, hydrogen or halogen; each of R1A, R2A, R3A, R6A, R7A, R8A and R9A is independently hydrogen or alkyl, aryl, alkylaryl, arylalkyl, heteroalkyl, heterocycle, alkylheterocycle or optionally substituted heterocycloalkyl; and each of R6B, R7B, R8B and R9B is independently hydrogen or alkyl optionally substituted with one or more hydroxy or halogen groups. |