http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2453970-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_34c608ecbd415271b7346a1433cdc439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7826e82a59639f553bfb024dfb2a0ea5 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B57-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-36 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B57-00 |
| filingDate | 2008-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_186222fa92b601f6211dd2059ca51303 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b6b6acb0bd5c7fb2e0c06374c74c1f84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c379ab9404040f5cc2a71b996343742 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d2ab84715d256387306323984a992549 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6383bac240e89b6d7d6d8fffd4b1194d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b20c63a04e0a68eead78457c97e91d5b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c9395cc5ac40a6affeba111ca85bb7c5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_91c29b2525b0abab647fe28574eb7292 |
| publicationDate | 2014-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2453970-T3 |
| titleOfInvention | Procedures for the resolution of the mixture of optical isomers, especially pinocembrin racemate |
| abstract | A method for the resolution of a mixture of optical isomers of pinocembrina, in particular a racemate of pinocembrina, said procedure comprising the following steps: (1) carrying out a derivatization reaction of a mixture of optical isomers of pinocembrina, which has been subjected to a protection of the phenolic hydroxyl group, with a chiral primary amine to provide a mixture of diastereoisomers, and carry out a separation of the mixture of diastereoisomers and optionally carry out a purification; and (2) desderivatize the separated diastereoisomers, and carry out a deprotection, and optionally carry out a purification, to obtain (R) - (+) - pinocembrina and / or (S) - (-) - pinocembrina, in the that said chiral primary amine is represented by the following general formula: chiral primary amine wherein, R1 is selected from -H, -CH3, -CH2CH3, -CH2CH2CH3, -CH (CH3) 2 or -CH2OH; R2 is selected from phenyl, benzyl, or phenyl or benzyl with a substituent on an aromatic ring thereof, -CH2OH-CH (OH) CH3, -CH (OH) C2H5, phCH (OH) - in which the substituent is selected of -CH3, -CH2CH3, -CH2CH2CH3, - (CH2) 3CH3, -CH (CH3) 2, -NO2, -CF3, -F, -CI, -I, -OH, -OCH3, -OC2H5, -COOCH3, -COOC2H5, -CONH2, -CONHCH3, -CONHC2H5, -CON (CH3) 2 or -CONHCH (CH3) 2; R3 has the same definition as that of R1 and R2 with the proviso that R3 does not have the same structure as R1 or R2 at the same time. |
| priorityDate | 2007-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 81.