http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2453616-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dcce39a20bef16c3f04497659caba40f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 |
| filingDate | 2008-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e31183c4ad55c3be84c163e3be00904f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8323f6238b8bd3978cfcf51a422c421d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be04f19cd91799a41b9861d6774e0fab http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a9c3f24052d8b9c17dc5bcbb8086ea4f |
| publicationDate | 2014-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2453616-T3 |
| titleOfInvention | Thiazolylidine urea and amide derivatives and procedures for their use |
| abstract | A compound of formula (I): ** Formula ** where R1 is hydrogen, methyl, phenyl, pyrazolyl or hydroxyl; R2 is hydrogen, alkyl, alkenyl,> = CH2 or> = CHRc where the alkyl group and the alkenyl group are substituted with 0, 1, 2 or 3 substituents independently chosen from the group consisting of alkoxycarbonyl, alkylcarbonyloxy, aryl, aryloxy , arylalkoxy, carboxy, cyano, cycloalkyl, haloalkoxy, heteroaryl, heterocycle, hydroxyl, nitro and RdReN-, where a group represented by R2 can be additionally substituted with 0, 1 or 2 groups chosen from halo and alkoxy; Rc is alkyl or halo; Rd and Re are each independently hydrogen, alkyl, alkoxyalkyl, aryl, arylalkyl, cyanoalkyl, heteroaryl, heteroarylalkyl, heterocycle or heterocycloalkyl; R3 is -G1-L-G2; G1 is aryl or heteroaryl; G2 is aryl, cycloalkyl, heteaoaryl, or heterocycle; L is a bond, O, alkylene, or -O-alkylene-; R4 is optionally substituted alkyl, cycloalkyl, heteroaryl, heterocycle or NR5R6; where, R5 and R6 are independently hydrogen, alkyl, (NRiRj) alkyl, alkynyl, aryl, heterocycloalkyl, cycloalkylalkyl, cyanoalkyl, cycloalkyl, alkoxyalkyl, arylalkyl, or heteroarylalkyl; and a is a single bond or a double bond; with the proviso that when R1 is hydroxyl or when R2 is a radical attached to the thiazole ring through an exocyclic double bond, then a is a single bond; and with the proviso that when a is a double bond, R1 is hydrogen, R2 is methyl, R3 is phenyl substituted with 3-haloalkyl, 3-halo, 3-haloalkoxy, 2,5-dihalo, 2,3-dihalo, 3,4-dihalo or 3,5-dihalo, then R4 is heterocycle; or a pharmaceutically acceptable salt, ester or amide thereof. |
| priorityDate | 2007-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1093.